Charles makes a number of great points here. One is that globalization has greatly benefited the elite in the USA. Another is that the US poverty policy has not kept up with our increasing national wealth, and the US poor are about as poor as they were a half century ago. He suggests that as a result, the large fraction of the US population that are poor see globalization primarily as threat and not opportunity.
He goes on to suggest that in many ways our fear of the rest of the world is depriving us of opportunities and wealth, and that our attitude is the basis of a major foreign policy problem.